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These receptors are significant regulators in the brain for other neurotransmitters like dopamine and glutamate. Dopamine is not only responsible for inducing pleasurable feelings but can affect sleep, mood, memory, attention and voluntary movement. Other drugs such as cocaine and methamphetamine act by amplifying the effects of dopamine receptors as well but on a way larger scale. While THC temporarily enhances dopamine levels CBD does not, it has only been found to be sporadic in research done on mice and rats mostly working as an inhibitor. More research is needed into why this is and how it only happens randomly.

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